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Research Makes Progress in Fight Against Flu
3 J% R3 Z8 ?9 \. `" ]抗击流感的研究进展
7 j* S2 L' u0 Y W" h4 P! bNew Study Shows Promise for Vaccine and Lifelong Immunity Against Strains of Flu
7 V; L5 e( n* `. ^( d- _最新研究预示:可能产生一种疫苗,该疫苗对流感病毒有终身免疫作用。: [) U7 E$ J* y, c' L9 q
It has been the Holy Grail of influenza research -- how to create just one vaccine that will protect against the hundreds of different flu strains that exist every year. With a new scientific discovery, researchers are now a major step closer to that goal.
" w" ?9 S9 f; `2 A+ y5 ~Holy Grail的流感研究重点在于:如何研制出一种对每年都出现的数百种不同株型的流感病毒均有保护作用的疫苗。新近一项科学发现使得研究者们向着这个目标跨出了重要的一步。
6 _9 D9 m+ D7 W" r K( B4 A. JResearchers identify a common weakness in a variety of influenza strains."We have identified a common Achilles heel of all influenza viruses and this really allows us then to work on a universal vaccine that will get us lifelong immunity," said Dr. Wayne Marasco, a researcher at the Dana-Farber Cancer Institute in Boston. ( N3 X, ]$ {( v) e4 ^3 K
研究者们发现所有不同流感病毒都有一个共有的脆弱点。“我们已经发现所有流感病毒都有一个要害点,这就允许我们研究出一种通用的、对我们有终生保护作用的疫苗” Wayne Marasco博士——位于波士顿的Dana-Farber癌症协会的一位研究者如是说。
* ?7 G* H* z7 C' B0 `: HResearchers have identified antibodies that inactivate the influenza virus before it has the chance to change itself. Drugs derived from the antibodies could both prevent and treat seasonal flu and have the potential to lead to a flu vaccine, putting an end to once-a-year shots and the need to reformulate vaccines each year, or match the changing flu strains in circulation. . F" e q' {4 Y$ j E7 s+ P
研究者们已经识别出在病毒有机会变异之前可使病毒失活的抗体。由抗体衍生的药物既可以预防、治疗季节性流感,还有可能导致流感疫苗的产生,这就可以结束每年一次的免疫注射,每年也不需要再重构疫苗或匹配流感流行中不断变化的病毒株型。
3 _1 r. U, B8 O! S3 C"Instead of having vaccines every year and developing immunity for that winter season, we now recognize we have the potential to actually have lifelong immunity if we did this correctly," Marasco said.& {) }% w4 ?6 q* e
Marasco说:“现在我们意识到,如果这能得以正确实施,我们就确实拥有终生免疫的潜在可能性,而不需要每年注射一次疫苗以构筑冬季的免疫力。” |
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