公卫人

 找回密码
 立即注册

QQ登录

只需一步,快速开始

查看: 5118|回复: 3

[分享] Methods and Applications of Statistics in Clinical Trials, Volume 2 (2014)

[复制链接]
sampson2010 发表于 2015-5-27 17:09:33 | 显示全部楼层 |阅读模式

注册后推荐绑定QQ,之后方才可以使用下方的“用QQ帐号登录”。

您需要 登录 才可以下载或查看,没有账号?立即注册

x
本帖最后由 sampson2010 于 2015-5-28 11:39 编辑 # V3 O& `6 O" w5 r$ R6 t3 P5 J
0 j$ b; S$ S3 F2 `* K
1118304764.jpg ; g* T5 W( L4 [. A. F4 B
( Q# m+ l( g9 n" y, g" _
Title: Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods- f4 M+ Z1 L( w; z3 x2 {! ]
Author(s): N. Balakrishnan
  N  d" i) K& b& w" A, H: [Publisher: Wiley1 L* X0 Q0 f& m( n7 X  q& `
Year: 2014       
+ ~; W9 h% ^) X  Y6 iEdition: 1
  y; H4 y+ O8 K! o0 e' t8 [Language: English* o7 U# I+ E/ ]3 J
Pages: 960& J$ }9 m: n) r) s6 n9 J3 P5 J
ISBN: 1118304764, 9781118304761
: d1 K3 l9 l7 g7 m4 pSize: 63 MB (65940955 bytes)       
' g8 j% ?' U) j, ?- [8 uExtension: pdf

, e; k/ \! I2 |4 B% S6 a! `$ v$ T4 D: _& `5 i( ?( ]

# w0 h, g# R) x& _$ ?0 {Description- v2 Q/ q1 K0 s5 `8 ~5 i+ p. N
7 l+ }1 o4 h) d. S  \9 Y
Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features:
# s# I8 m! F8 Y+ D8 s+ f2 k' T# ~
; }& }- v$ P; N$ B6 ?2 F; j! i1 J- \• Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems6 S, q: S2 h; ~6 E  f1 L; u* c6 ~  V
" Z) Q! @4 Y& m; i
• Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index
+ Q9 p# D' a# @) M/ x, y8 P. I5 I+ `6 P0 c( g
• Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials2 s% V* R5 W( v9 A+ F- Y6 e
; x! ~9 e2 R# @

* f5 l8 c2 k# C( ?/ E- X/ STable of Contents3 O, I, ~" O) Z9 J
% Z- k! Q9 e6 M. M
Contributors xix
2 Y1 R7 D  \+ a9 P3 m* R0 R; t; Y! G) ?3 r  u
Preface xxiii
! w* }8 U# I. Y# y1 ^: Z3 h% z6 f+ [
1 Analysis of Over- and Underdispersed Data 1
' O" V6 Y9 `/ U$ ?% \0 h! s$ u% J/ `, V5 d3 }
2 Analysis of Variance (ANOVA) 10
' w9 H$ A7 v0 v! n2 p8 H7 \8 ~  U+ O5 d1 H7 L( n& z
3 Assessment of Health-Related Quality of Life 26/ g# B5 g5 z7 S6 o5 }2 P
0 Y4 K& ]" ~# ?( ^" [
4 Bandit Processes and Response-Adaptive Clinical Trials: The Art of Exploration Versus Exploitation 40
7 D$ h9 w; q' M4 ^5 j' u2 v9 |( |; M, G. z3 Z) E
5 Bayesian Dose-Finding Designs in Healthy Volunteers 515 \# j8 G* V* U+ L6 S! _; B, J

4 t4 u9 `8 w/ S' L! F6 q( s- V6 Bootstrap 62, R; J$ _/ c; J/ `+ u8 _4 J; E; i
  q7 G) C- e6 X" w
7 Conditional Power in Clinical Trial Monitoring 102, t. a! H% N2 L" m
* f% [7 Q& T$ {4 a+ L% ?
8 Cost-Effectiveness Analysis 111
& ]" G; ], u1 D+ ^# v6 m' |; k* q4 o& D2 S
9 Cox-Type Proportional Hazards Models 126
; C7 P0 I2 l" I0 J0 e  b: p7 w& M0 Y7 L" D7 p- e
10 Empirical Likelihood Methods in Clinical Experiments 146
! ~5 A1 b6 l  f' @8 E. }9 Y  ~4 \
3 _" u+ \/ f1 e8 H* x0 X3 R11 Frailty Models 166
! a. G* ?* _3 V' V$ U) J6 Z
( f- M2 ~6 t1 G/ d, ~12 Futility Analysis 174
5 g, e9 }; o8 I9 i* c- ^* i4 Z+ Q4 j, l& f" w  x" H. J7 {
13 Imaging Science in Medicine I: Overview 187! J$ E2 |# p+ _& j! Y; C

5 n' [, k; Y. h# u- r, M9 B) Q6 G. k14 Imaging Science in Medicine, II: Basics of X-Ray Imaging 2130 y/ P; N8 S4 x1 X" T% |; p; E

0 j4 t' M2 J+ n/ s15 Imaging Science in Medicine, III: Digital (21st Century) X-Ray Imaging 264
: t: Y  {" y& P% `3 z
9 _: J% v' J4 i4 m+ s: m  B6 l16 Intention-to-Treat Analysis 313
: F% C) o6 n' a8 R; }0 M
* g7 \9 S4 s- ]17 Interim Analyses 3239 [* M$ V/ t; d8 B
, S7 X+ h1 ^. T
18 Interrater Reliability 334
) @6 g+ n  w7 p( @
+ S8 ^/ B" V' {9 @+ _8 Y19 Intrarater Reliability 340
4 r! D+ \! h. O9 A; T* h4 w7 d' L# @5 F: L/ s: P+ q% F
20 Kaplan-Meier Plot 357
4 n# |: e( K1 `, C& U) C4 k' c& V  E( J
21 Logistic Regression 365
$ K/ F4 v6 ^& a6 a0 E" U  p: |* T
22 Metadata 380
* d8 N# H* r  G) m* E2 ^! `& Q+ S9 g7 N
23 Microarray 392  }6 w, Y$ v) N) h3 T
7 s3 b6 c/ H$ K) Z# p
24 Multi-Armed Bandits, Gittins Index, and Its Calculation 416
& Z6 e  n5 O. G: q; A9 x2 P* A/ X4 T# V, J
25 Multiple Comparisons 436
# [/ ]; z5 u% e; N& i2 H6 `+ g& x! R! @& _/ u
26 Multiple Evaluators 446
* ?( V+ R8 E6 q+ K, c: ~) y! |
# c4 A. [* d& K) n0 l& _27 Noncompartmental Analysis 457
  D( k/ I) t  ^% M( e
, E. B- @1 e6 w7 X8 c. A% L! C28 Nonparametric ROC Analysis for Diagnostic Trials 483
9 W9 ~7 d9 `" O' l# |  B" l" s+ Q0 }& j5 H! w: q, S5 s$ @3 Y
29 Optimal Biological Dose for Molecularly Targeted Therapies 4960 r" U# Y* r" c1 m! x3 D$ c

) }4 a; y7 f/ E! c( V& Q6 z30 Over- and Underdispersion Models 506
7 A) y# p; O* F+ e3 S, ?, P' b  ?: ]% W  H3 b
31 Permutation Tests in Clinical Trials 527/ u; J' I2 X% f! P. h- [
2 l+ \4 r. r1 E3 J( Z
32 Pharmacoepidemiology, Overview 536: m7 J! m; @( X9 L- ]& o% Y

; s" P$ T0 S& l' e4 A! \33 Population Pharmacokinetic and Pharmacodynamic Methods 551) ^0 L# h0 h! }9 c0 P  A9 y6 W
- ?3 E& O4 O4 m5 z
34 Proportions: Inferences and Comparisons 570
3 H: M' {$ z( i/ f. h( ?* m2 Q1 m& d! h
35 Publication Bias 5951 M6 D& t' T) p7 R9 N
" g2 W. A# ]9 L1 P
36 Quality of Life 6080 Z, L: Z" [% B6 X* b( @, [% l4 u

; G$ G6 {$ O0 s# l. `8 a37 Relative Risk Modeing 622& v9 _. T  V. f( s
; ?, w5 `  o0 A0 g. a
38 Sample Size Considerations for Morbidity/Mortality Trials 633' P  O( I/ F8 D0 v& _
# S  c' O* f4 Y. B! j# _3 R
39 Sample Size for Comparing Means 6426 ~4 n: T5 a9 H6 g8 C) n4 S' E9 Z

# \7 q7 ^3 S+ F/ ^' B40 Sample Size for Comparing Proportions 653' ~' N7 d1 C; C' P6 ~
2 P  f" a+ G* I
41 Sample Size for Comparing Time-to-Event Data 6647 `/ b! ]3 N# `% a& Y  ~, F

/ W  G4 R+ @! F; ^* m' F. \0 L42 Sample Size for Comparing Variabilities 672! ^( T+ m, H# H6 ?
, S9 F* B, U4 Q" R$ {$ {; U
43 Screening, Models of 6899 G( V9 i5 C6 q+ n3 w. I. W

6 {3 \) [/ Q" x+ E, K44 Screening Trials 721
# s+ R7 K3 L' i# l' R# M! R
" n- @, L4 W" x% ]  E5 u( ^& {" D45 Secondary Efficacy End Points 731
8 C( P. V/ u5 E3 E1 Z/ q1 B' ?
. p4 @( J$ j9 R8 K! y/ Q: F46 Sensitivity, Specificity, and Receiver Operator Characteristic (ROC) Methods 740
- U# t- l! m1 d# n, T+ t9 _  P$ K: b  [
47 Software for Genetics/Genomics 752
$ u6 z& p0 b4 ]2 q
( M1 q: g- W! r' j; E6 Q+ p4 n5 X8 \48 Stability Study Designs 778
6 _  w, f0 _& X- h
& _; m. t% }5 p! j" M49 Subgroup Analysis 793. o3 G4 q0 C, B

" y; I% x$ k5 n2 m50 Survival Analysis, Overview 802( L4 L$ v) o* c! a7 {5 r
, ]5 k3 Z# ^: m, @7 O: `& ~9 O4 ^
51 The FDA and Regulatory Issues 815
0 m# K8 V% Z! x  U1 x% ]. s" `& @
; q* Q, o. x; L$ V) z: m52 The Kappa Index 836
6 q  b: n, A1 e: _0 i- L! ]4 u( R  r7 }
53 Treatment Interruption 8469 q/ `+ [1 Y7 ?- r! t  I/ z6 x
+ F0 o! y+ Y; g
54 Trial Reports: Improving Reporting, Minimizing Bias, and Producing Better Evidence-Based Practice 860! [6 R3 d& Z6 N+ ~' C3 a6 Z: ]

4 \5 p- C2 I/ J, t$ X55 U.S. Department of Veterans Affairs Cooperative Studies Program 876
9 Y; p" e: U# A( E5 x0 L$ ~9 ^# v8 R" R
56 Women's Health Initiative: Statistical Aspects and Selected Early Results 901
: a$ K% k( z, T5 V6 k' B
1 U* G0 e* F/ }7 @  W6 n57 World Health Organization (WHO): Global Health Situation 914
0 e, O6 \% o( D8 C3 r) @, Z* Q, U* X& G$ s% C, w) M, y& a, H
Index 925& V) i  O/ H6 D. u# t$ u

" P: }! Q$ O7 i0 }5 s! \+ m' j! `0 T" U1 n, o& p8 K1 S" d
Author Information
3 K) L6 H1 m# ^  `0 z/ g9 E9 Q& z  Z  M
9 B2 `2 y/ [: F) a! N* {N. BALAKRISHNAN, PHD, is Professor in the Department of Mathematics and Statistics at McMaster University, Canada. He is the author of over twenty books and is the coeditor of Encyclopedia of Statistical Sciences, Second Edition, also published by Wiley.
8 B. T2 {9 \3 B' w* {: G. t' f
4 O2 e1 A1 K4 r! M! f+ p4 y  H0 Y4 t
* V# v9 l) G" e0 g
PDF附件较大,请点击下载:+ r  n: \+ D2 t
Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods
; F6 Z6 ~& @* `$ J! }2 }, H
, {; U: z! I* [

7 n0 ~) H3 p* K! j( z: c- P: X# ]* b8 ~, C7 w% h
111830473X.jpg ' _9 y$ \5 [$ h% a5 D
& H& w! F% w7 `3 Z* s4 R* |
Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs2 S5 e4 G& x) t$ y1 k$ U. N4 e4 G( j
' U7 ~3 |$ J5 y
~~COMMING SOON~~4 X- _3 u) w& T
! K7 E5 @' A5 n& H- q/ H+ K" f# Q

本帖被以下淘专辑推荐:

renm 发表于 2015-6-29 14:56:50 | 显示全部楼层
楼主强大!太谢谢啦!
回复

使用道具 举报

chf521chf521 发表于 2015-8-21 21:16:03 | 显示全部楼层
感谢,感谢,必须学习
回复

使用道具 举报

hprxq 发表于 2016-4-17 19:55:56 | 显示全部楼层
谢谢了,下载了
回复

使用道具 举报

您需要登录后才可以回帖 登录 | 立即注册

本版积分规则

手机版|会员|至尊|接种|公卫人 ( 沪ICP备06060850号-3 )

GMT+8, 2024-3-29 07:30 , Processed in 0.071352 second(s), 8 queries , Gzip On, MemCached On.

Powered by Discuz! X3.4

© 2001-2023 Discuz! Team.

快速回复 返回顶部 返回列表