Advances in Clinical Trial Biostatistics - Nancy L. Geller

Advances in Clinical Trial Biostatistics - Nancy L. Geller


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【书名】 ADVANCES IN CLINICAL TRIAL BIOSTATISTICS
  e1 c# n7 D- I: U5 E【作者】NANCY L. GELLER
" k! F6 m4 c8 O【出版社】 by Marcel Dekker,
【版本】1
7 X5 K( n4 G: D/ [/ ^9 \【出版日期】2004
! z$ x: @; P2 v8 d【文件格式】PDF
【文件大小】2.14 Mb
$ S+ t8 j" F" X0 B# Z【页数】 278 including cover
【ISBN出版号】ISBN: 0-8247-9032-4
【资料类别】统计学，textbook
. h0 I. q$ S, ~) n: k/ @【市面定价】89.1 USD
【扫描版还是影印版】original
【是否缺页】complete
0 t8 Z. F, ~- A6 Q: Q4 m2 B* M, h【关键词】biostatistics, clinical trial
【内容简介】From aspects of early trials to complex modeling problems, Advances in Clinical Trial Biostatistics summarizes current methodologies used in the design and analysis of clinical trials. Its chapters, contributed by internationally renowned methodologists experienced in clinical trials, address topics that include Bayesian methods for phase I clinical trials, adaptive two-stage clinical trials, and the design and analysis of cluster randomization trials, trials with multiple endpoints, and therapeutic equivalence trials. Other discussions explore Bayesian reporting, methods incorporating compliance in treatment evaluation, and statistical issues emerging from clinical trials in HIV infection.
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【目录】
Contents
Series Introduction
Preface
9 x' E  y+ I5 U7 IContributors
! f( l8 {0 B4 R: rPart I METHODS FOR EARLY TRIALS
1. Bayesian Methods for Cancer Phase I Clinical Trials
2. Design of Early Trials in Stem Cell Transplantation:
A Hybrid Frequentist-Bayesian Approach

Part II METHODS FOR RANDOMIZED TRIALS
3. Design and Analysis of Therapeutic Equivalence Trials
- g9 x, a+ I$ n! w- `5 s4. Adaptive Two-Stage Clinical Trials
# m( \. C9 Y# g4 {( w5. Design and Analysis of Cluster Randomization Trials
6. Design and Analysis of Clinical Trials with Multiple
( \( w: ^8 r+ z9 WEndpoints
7. Subgroups and Interactions
8. A Class of Permutation Tests for Some Two-Sample
Survival Data Problems
9. Bayesian Reporting of Clinical Trials

% R1 M8 j( L, [Part III MORE COMPLEX PROBLEMS
) T: L+ m% F" v1 j10. Methods Incorporating Compliance in Treatment
Evaluation
11. Analysis of Longitudinal Data with Missingness
$ g+ O1 \  g8 e# V* p" g12. Statistical Issues Emerging from Clinical Trials in HIV
Infection

3 q, h6 G7 H* C, L, u4 v6 \; lIndex of Abbreviations
Index of Clinical Trials Used as Examples
Subject Index
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+ h" k# k2 J# W( u【原创书评】Clinical trial 與實驗室bench實驗不同之處在於試驗的對象是人,而人都會希望自己得到最好的治療. 因此又發展出許多不同的實驗設計方法,特別是在符合Declaration of Helsinki的普世價值之下. 這本書討論的內容相對來說比較屬於介紹統計建模的工具,前面先用例題作出dose-response curve. 後面是對一些特定情況介紹一些檢定工具. 這本書比較屬review 性質並沒有很多公式推導的來源, 有作過一些這類分析的朋友可能比較能領會; 不熟悉這塊的人可能會望書興嘆(沒有sas or R code).
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Review
recommend[ed].written in a style that explains the methods rather than one that simply trieds to impress you with how clever the authors are.
-Pharmaceutical Statistics

Twenty contributions provide a wide range of experience in the disciplinewell written, clear and concise...provides an excellent source of reference material...provides interesting reading with new methodology clearly explainedmakes an important contribution to the fieldfigures, tables, examples, summaries, discussions and conclusions are well presented. I liked the useful index of clinical trials and index of abbreviations at the end of the bookexamples provide for interesting reading. I recommend this book. It makes a worthwhile addition to any medical science and/or statistics library.
# X% z7 \; I9 W7 l-ISCB News, December 2004
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% a7 h# i# B! u* n5 @/ r! `% d+ A) sThis book provides excellent survey articles on most commonly used biostatistical tools for clinical research. The articles cover the whole range of clinical research This book is recommended for biostatistics graduate students and practitioners. I support this recommendation.
-Zentralblatt MATH
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This volume is a collection of 12 excellent chapters by researchers with extensive experience with research in biostatistics. The researchers are knowledgeable with both the underlying theory and the practical difficulties encountered in clinical trials research. The book is a recommended purchase for research libraries.
-Journal of Mathematical Psychology, Vol. 49, 2005
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As a summary of some of the currently most modern approaches to design and analysis, this is a welcome addition for both personal and institutional libraries.
Clinical Trials
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contains a dozen research articles by experts illustrating modern (Bayesian and frequentist's) statistical approaches to design and analysis for drug development. Biostatisticians and clinical scientists will like this book and find it highly useful.
' a# O  z" g! P8 W-Journal of Statistical Computation and Simulation, Vol. 75, No. 9, Sept. 2005
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  |3 `5 j0 B' H; eProduct Description
# U* T. u) Y' K5 Y8 Q2 WFrom aspects of early trials to complex modeling problems, Advances in Clinical Trial Biostatistics summarizes current methodologies used in the design and analysis of clinical trials. Its chapters, contributed by internationally renowned methodologists experienced in clinical trials, address topics that include Bayesian methods for phase I clinical trials, adaptive two-stage clinical trials, and the design and analysis of cluster randomization trials, trials with multiple endpoints, and therapeutic equivalence trials. Other discussions explore Bayesian reporting, methods incorporating compliance in treatment evaluation, and statistical issues emerging from clinical trials in HIV infection.
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2 }( x& A+ D* \: q/ V下载地址
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既然书名都写出来了，威望就不要设那么高嘛

回复 i]epiman 的帖子[/b
绝对的好人啊

好书，已经下载收下，就是有点儿贵哦。谢谢。