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[商城] 慢性病分子流行病学 复印本

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epiman 发表于 2018-11-22 17:23:08 | 显示全部楼层 |阅读模式

慢性病分子流行病学 复印本

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Molecular Epidemiology of Chronic Diseases 1st Edition
详情:https://www.amazon.com/dp/0470027436
Hardcover: 384 pages
Publisher: Wiley; 1 edition (June 9, 2008)
Language: English
ISBN-10: 0470027436

Review

"I think this is an excellent book—I recommend it to anyoneinvolved in molecular epidemiology.... The 26 chapters are writtenby topic specialists, in an explanatory, easy to read style."(BTS Newsletter, Summer 2009)

"This text provides an accessible and useful handbook for theepidemiologist who wants to survey the field, to become betterinformed, to look at recent developments and get some background onthese or simply to appreciate further the relatively rapid changesin informatic and analytical technologies which increasingly willserve and underpin future epidemiological studies. One of thestrengths in this book is the extensive array of practicalillustrative examples, and it would also in my opinion have usefulpotential as a teaching text." (American Journal of HumanBiology, March 2009)

From the Back Cover

With the sequencing of the human genome and the mapping of millionsof single nucleotide polymorphisms, epidemiology has moved into themolecular domain. Scientists can now use molecular markers to trackdisease-associated genes in populations, enabling them to studycomplex chronic diseases that might result from the weakinteractions of many genes with the environment. Use of theselaboratory-generated biomarker data and an understanding of diseasemechanisms are increasingly important in elucidating diseaseaetiology.

Molecular Epidemiology of Chronic Diseases crosses thedisciplinary boundaries between laboratory scientists,epidemiologists, clinical researchers and biostatisticians, and isaccessible to all these relevant research communities in focusingon practical issues of application, rather than reviews of currentareas of research.

    Covers categories of biomarkers of exposure, susceptibilityand disease
    Includes chapters on novel technologies: genomics,transcriptomics, proteomics and metabonomics, which areincreasingly finding application in population studies
    Emphasizes new statistical and bioinformatics approachesnecessitated by the large data sets generated using these newmethodologies
    Demonstrates the potential applications of laboratorytechniques in tackling epidemiological problems while consideringtheir limitations, including the sources of uncertainty andinaccuracy
    Issues such as reliability (compared to traditionalepidemiological methods) and the timing of exposure arediscussed
    Practical elements of conducting population studies, includingbiological repositories and ethics, are explored

Molecular Epidemiology of Chronic Diseases provides aneasy-to-use, clearly presented handbook that allows epidemiologiststo understand the specifics of research involving biomarkers,andlaboratory scientist to understand the main issues ofepidemiological study design and analysis. it also provides auseful tool for courses on molecular epidemiology using manyexamples from population studies to illustrate key concepts andprinciples.
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